1.教育状况

2013.09.01-2017.06.01，东北农业大学，动物科学专业，学士；

2017.09.01-2020.06.01，东北农业大学，动物营养与饲料科学系，硕士研究生；

2020.09.01-2024.06.01，东北农业大学，动物营养与饲料科学系，博士研究生；

2.工作经历

2024.07-至今：东北农业大学动物科学技术学院，副教授，硕士研究生导师

代表性论文（第一作者或通讯作者）：

[1] Lu Zhao, Jiaoyu Xin, Mingyang Hu, Chenyu Xue*, Na Dong*. Programmable microbial therapeutics: Advances in engineered bacteria for targeted in vivo delivery and precision medicine [J]. Journal of Advanced Research 2025.

[2] Mingyang Hu, Yuwen Li, Sina Cha, Lu Zhao, Can Liu, Mingrui Sui, Chenyu Xue*, Na Dong*. Development of targeted antimicrobial peptides for Escherichia coli: Combining phage display and rational design for food safety application [J]. Food Chemistry, 2025, 470:142685.

[3] Yutong Xue, Mingyang Hu, Sina Cha, Chenyu Xue*, Na Dong* . Precision therapeutics for inflammatory bowel disease using engineered probiotics: Strategies and optimization[J]. Acta Biomaterialia, 2025.

[4] Jianing Tu ,Chongpeng Bi, Ying Li , Shuyu Zhang , Zichuan An , Yueyang Han , Yupu Wang ,Anshan Shan , Chenyu Xue* , Na Dong* , Jiali Wang*. Stearoyl-CoA desaturase 1-mediated fatty acid metabolism inhibition drives intestinal injury in offspring exposed to maternal acetamiprid. International Journal of Biological Macromolecules 320(2025) 145839.

[5] Mingyang Hu, Yuwen Li, Lu Zhao, Sina Cha , Yuxin Fang, Chenyu Xue*, Na Dong*. Thymidylate kinase-targeted antimicrobial peptides via phage display: A novel strategy against gram-negative bacteria [J]. Journal of Medicinal Chemistry, 2025, 68:5488-502.

[6] Wenpeng Wu, Shuyue Wang, Chenyu Xue*, Na Dong*. Role of gut microbiota metabolites in maintaining intestinal health and preventing weaning-associated diarrhea in piglets [J]. Animal Nutrition, 2025.

[7] Jiaxin Liu, Weichen Hong, Zhendong Sun, Shuyu Zhang, Chenyu Xue*, Na Dong*. The gut-lung axis: effects and mechanisms of gut microbiota on pulmonary diseases [J]. Frontiers in Immunology, 2025.

[8] Lu Zhao, Mingyang Hu, Yuwen Li, Jiaoyu Xin, Yuxin Fang, Chenyu Xue*, Na Dong*.Production and Functional Evaluation of Recombinant Active Peptide RH in Pichia Pastoris: Protection Against Escherichia Coli Induced Cell Death.Probiotics and Antimicrobial Proteins,2025.

[9] Chenyu Xue, Hongpeng Jia, Rujing Cao, Wenjie Cai, Weichen Hong, Jianing Tu, Songtao Wang, Qianzhi Jiang, Chongpeng Bi, Anshan Shan, Na Dong*. Oleanolic acid improved intestinal immune function by activating and potentiating bile acids receptor signaling in E. coli-challenged piglets.Journal of Animal Science and Biotechnology, 2024, 15(1): 79.

[10] Chenyu Xue, Na Dong*, Anshan Shan*. Putative role of STING-mitochondria associated membrane crosstalk in immunity.Trends in immunology, 2022, 43(7): 513-522.

[11] Chenyu Xue, Hao Lv, Ying Li, Na Dong*, Jiale Zhou, Yanhui Wang, Baoming Shi, Anshan Shan*. Oleanolic Acid Reshapes the Gut Microbiota and Alters Immune-related Gene Expression of Intestinal Epithelial Cells.Journal of the Science of Food and Agriculture, 2022, 102(2): 764-773.

[12] Chenyu Xue, Ying Li, Hao Lv, Lei Zhang, Chongpeng Bi, Na Dong*, Anshan Shan*, Jiali Wang*. Oleanolic Acid Targets the Gut-Liver Axis to Alleviate Metabolic Disorders and Hepatic Steatosis.Journal of Agricultural and Food Chemistry, 2021, 69(28): 7884-7897.

[13] Na Dong#, Chenyu Xue#, Lei Zhang, Tingting Zhang, Chensi Wang, Chongpeng Bi, Anshan Shan*.Oleanolic acid enhances tight junctions and ameliorates inflammation in Salmonella typhimurium-induced diarrhea in mice via the TLR4/NF-κB and MAPK pathway..Food & function, 2020, 11(1): 1122-1132..

在研课题

1. 国家自然基金青年科学基金项目（C类），2026.01-2028.12，主持

2. 黑龙江省"优秀青年教师基础研究支持计划"项目，2025.12-2028.12

3. 黑龙江省自然科学基金校（院）企合作项目，2026.01-2027.12，主持

4. 东北农业大学高层次人才引进项目，2024.09-2026.09，主持