1．教育状况

2001.09-2005.06：黑龙江八一农大动科院，学士

2006.09-2009.06：黑龙江八一农垦大学基础兽医学专业，硕士研究生

2009.09-2013.06：东北农大动物营养与饲料科学专业，博士研究生

2015.10-2018.12：东北农大动物医学院，博士后

2．工作经历

2015.07-2016.08 东北农业大学新农村发展研究院 讲师

2016.09-2022.08 东北农业大学动物科学技术学院 副教授

2022.09-至今   东北农业大学动物科学技术学院 教授

代表性论文

Zijiang, Yang, Shengchen, Wang, Honggui, Liu, Shiwen, Xu. (2021). MAPK/iNOS pathway is involved in swine kidney necrosis caused by cadmium exposure. Environmental Pollution, 274, 116497.

Ji, W.B., Li, X., Zhang, X.H., Liu, R.Z., Shu,Y.F., Cheng, Z., Bi,Y.J., Liu, H.G., Bao, J. . Effects of two different early socialization models on social behavior and physiology of suckling piglets. Applied Animal Behaviour Science,2021， 243, 105436.

Wang, H., Zeng, X., Zhang, X., Liu, H., Xing, H. (2021). Ammonia exposure induces oxidative stress and inflammation by destroying the microtubule structures and the balance of solute carriers in the trachea of pigs. Ecotoxicology and Environmental Safety, 212, 111974.

Ji, W.B., Bi, Y.J., Cheng, Z., Liu, R.Z., Zhang, X.H., Shu, Y.F., Li, X., Bao, J., Liu, H.G. . Impact of early socialization environment on social behaviour, physiology and growth performance of weaned piglets. Applied Animal Behaviour Science,2021， 238, 105314.

Yiming, Z., Hang, Y., Bing, S., Hua, X., Bo, H., Honggui, L., Shu, L. (2021). Antagonistic effect of VDR/CREB1 pathway on cadmium-induced apoptosis in porcine spleen. Ecotoxicology and Environmental Safety, 209, 111819.

Bi, Y.J., Liu, R.Z., Ji, W.B., Wei, H.D., Pan, L., Li, J.H., Li, X., Zhang, R.X., Liu, H.G., Bao, J.. Early social contact alters the community structure and functions of the faecal microbiome in suckling-growing piglets. Animal, 2021，15(12), 100393.

Zhao, X., Li, X., Wang, S., Yang, Z., Liu, H., Xu, S. Cadmium exposure induces mitochondrial pathway apoptosis in swine myocardium through xenobiotic receptors-mediated CYP450s activation. Journal of Inorganic Biochemistry,2021， 217, 111361.

Zhao, X., Wang, S., Li, X., Liu, H., Xu, S. Cadmium exposure induces TNF-α-mediated necroptosis via FPR2/TGF-β/NF-κB pathway in swine myocardium. Toxicology, 453, 152733.

Wei, Cui, Sitong, Zhou, YuLin, Wang, Xu, Shi, Honggui, Liu, Cadmium exposure activates the PI3K/AKT signaling pathway through miRNA-21, induces an increase in M1 polarization of macrophages, and leads to fibrosis of pig liver tissue. Ecotoxicology and Environmental Safety,,2021，228, 113015.

Chen, J., Shao, B., Wang, J., Shen, Z., Liu, H., Li, S.. Chlorpyrifos caused necroptosis via MAPK/NF-κB/TNF-α pathway in common carp (Cyprinus carpio L.) gills. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology,2021,249, 109126.

Xu, S., Xiaojing, L., Xinyue, S., Wei, C., Honggui, L., & Shiwen, X. (2021). Pig lung fibrosis is active in the subacute CdCl2 exposure model and exerts cumulative toxicity through the M1/M2 imbalance. Ecotoxicology and Environmental Safety, 225, 112757.

Hengyi, Zhang, Wenbo, Ji, Xin, Li, Yanru, Feng, Jing, Wang, Honggui, Liu, Jun, Bao. Immunosuppression, oxidative stress, and apoptosis in pig kidney caused by ammonia: Application of transcriptome analysis in risk assessment of ammonia exposure. Toxicology and Applied Pharmacology,2021, 428, 115675.

Jiafang Li, Qian Han, Runze Liu, Pengfei Wen, Wenbo Ji, Lei Pan, Chao Wang, Peng Zhao, Honggui Liu, Jun Bao *. Effects of environment and breed on growth performance and meat quality of fattening pig, Animal Welfare, 2020, 29(2):177-184.

Honggui Liu, Ran Yi, Chao Wang, Peng Zhao, Mingyue Zhang, Shiwen Xu, Jun Bao. Behavior and physiology of two different sow breeds in a farrowing environment during late 35-day lactation. PLOS ONE,2018,13(5), e0197152.

在研课题

横向课题：发酵床模式下不同品种育肥猪的生产状况评估 2019.8—2020.12.主持

黑龙江省自然科学基金面上项目:改善妊娠期环境对提高母猪母性能力机制的研究 2016.7-2019.7.主持

农业农村部生猪产业技术体系子课题:饲养工艺及饲养管理，2017-2021，主持