男，汉族，1993年2月生，中共党员。2021年以高层次引进人才入职东北农业大学，主持国家自然科学基金青年项目、黑龙江省优秀青年科学基金等课题8项。发表学术论文40篇，其中SCI论文30篇，总IF 251.2，总被引1200余次，H-index21。以第一/通讯作者在Science Advances、ACS Nano、Drug Resistance Updates、Chemical Engineering Journal、Small、Acta Biomaterialia、Food Chemistry、Journal of Medicinal Chemistry、Journal of Nutrition、科学通报等发表论文23篇，其中IF>10论文6篇，中科院1区Top期刊11篇，中国科技期刊卓越计划论文6篇。申请国家发明专利27项，授权25项。出版著作1部。作为主要完成人获黑龙江省科学技术进步奖一等奖、黑龙江省高等教育教学成果奖二等奖。Chem、ACS Nano、Journal of Advanced Research、Advanced Functional Materials等期刊审稿人。

1.学习经历

2010.09-2014.06：东北农业大学动物科学专业，学士

2014.09-2017.06：东北农业大学动物营养与饲料科学专业，硕士

2017.09-2021.06：东北农业大学动物营养与饲料科学专业，博士

2.工作经历

2021.10-至今：东北农业大学动物科学技术学院，副教授，硕士研究生导师

2022.04-至今：东北农业大学生命科学学院微生物学，博士后

2024.05-2025.03：东北农业大学“畜牧学”一级学科秘书

2024.12-至今：东北农业大学动物科学技术学院，博士研究生导师

2025.04-至今：农业农村部科技发展中心，项目管理专员

3.在研课题

[1]黑龙江省自然科学基金联合培育项目，PL2025C016，2026.01-2028.12，主持。

[2]国家自然科学基金青年科学基金项目，32402788，2025.01-2027.12，主持。

[3]黑龙江省博士后科学基金特别资助项目，LBH-TZ2403，2025.01-2027.12，主持。

[4]中国博士后科学基金会面上资助（二等），2022M720694，2023.01-2024.12，主持。

[5]黑龙江省博士后科学基金面上项目（一等），LBH-Z22007，2023.01-2024.12，主持。

[6]黑龙江省自然科学基金优青项目，YQ2022C015，2022.07-2025.07，主持。

4.代表性成果（本人名字处可标粗；按文章（第一作者或通讯作者）、专著、专利、品种、标准等顺序列出，共计10项以内）：

[1] Hongrui Guan, Jianan Pang, Mengcheng Wang, Haoran Deng, Yongjie Zhu, Licong Zhang, Na Dong, Anshan Shan*,Changxuan Shao*. Antimicrobial peptides: Source, biological function and intestinal regulation of piglets.Journal of Nutrition,2025, 155(9), 2871-2884.

[2] Yongjie Zhu^#, Bowen Li^#, Wanying Xu, Yuanmengxue Wang, Guoyu Li, Chongpeng Bi, Anshan Shan*,Changxuan Shao*. Association of idealized amphiphiles and protease inhibitors: Conferring antimicrobial peptides with stable antibacterial activity under physiological conditions to combat multidrug-resistant bacteria.Drug Resistance Updates,2025, 79, 101183.

[3] Yongjie Zhu, Wanying Xu, Wenwen Chen, Bowen Li, Guoyu Li, Haoran Deng, Licong Zhang,Changxuan Shao*, Anshan Shan*. Self-assembling peptide with dual function of cell penetration and antibacterial as a nano weapon to combat intracellular bacteria.Science Advances,2025, 11(6), eads3844.

[4] Guoyu Li, Haoran Deng, Wanying Xu, Wenwen Chen, Zhenheng Lai, Yongjie Zhu, Licong Zhang,Changxuan Shao*, Anshan Shan*. Combating Antibiotic-Resistant Bacterial Infection Using Coassembled Dimeric Antimicrobial Peptide-Based Nanofibers.ACS Nano,2025, 19(3), 3155-3171.

[5] Guoyu Li, Wenwen Chen, Hongrui Guan, Zhenheng Lai,Changxuan Shao*, Anshan Shan*. Dendritic Antifungal Peptides as Potent Agents against Drug-Resistant Candida albicans and Biofilm.Journal of Medicinal Chemistry,2025,68(3):3373-3385.

[6] Haoran Deng, Shaohua Zhang, Yanxue Fu, Na Dong, Chongpeng Bi, Anshan Shan*,Changxuan Shao*. Advances in the delivery and application of antimicrobial peptide-based nanomaterials.Chemical Engineering Journal,2024, 496, 154232.

[7]Changxuan Shao^#, Yuanmengxue Wang^#, Guoyu Li, Hongrui Guan, Yongjie Zhu, Licong Zhang, Na Dong, Anshan Shan* . Novel Design of Simplified β-Hairpin Antimicrobial Peptide as a Potential Food Preservative Based on Trp-Pocket Backbone.Food Chemistry, 2024, 448, 139128.

[8]Changxuan Shao^#, Qiao Jian^#, Bowen Li, Yongjie Zhu, Weikang Yu, Zhongyu Li, Anshan Shan^*. Ultrashort All-Hydrocarbon Stapled αHelix Amphiphile as a Potent and Stable Antimicrobial Compound.Journal of Medicinal Chemistry, 2023, 66, 11414-11427.

[9]Changxuan Shao^#, Yongjie Zhu^#, Qiao Jian, Zhenheng Lai, Peng Tan, Guoyu Li, Anshan Shan^*. Cross-Strand Interaction, Central Bending, and Sequence Pattern Act as Biomodulators of Simplified β-Hairpin Antimicrobial Amphiphiles.Small, 2021, 17(7), 2003899.

[10]Changxuan Shao, Haotian Tian, Tianyu Wang, Zhihua Wang, Shuli Chou, Anshan Shan^*, Baojing Cheng. Central β-turn Increases the Cell Selectivity of Imperfectly Amphipathic α-helical Peptides.Acta Biomaterialia, 2018, 69, 243-255.