1．教育状况

2008.09-2012.06：东北农业大学动物科学专业，学士

2012.09-2015.06：东北农业大学动物营养与饲料科学专业，硕士

2021.09-至今：东北农业大学动物营养与饲料科学专业，博士

2．工作经历

2015.09-2017.08：东北农业大学动物科学技术学院，助理实验师2019.09-2023.08：东北农业大学动物科学技术学院，实验师

2023.09-至今：东北农业大学动物科学技术学院，高级实验师

代表性论文：

[1]Zhang, L., Zhang, J., Zang, H., Yin, Z., Guan, P., Yu, C., Shan, A., & Feng, X. (2024). Dietary pterostilbene exerts potential protective effects by regulating lipid metabolism and enhancing antioxidant capacity on liver in broilers. Journal of Animal Physiology and Animal Nutrition, 108(4), 921-933.https://doi.org/10.1111/jpn.13941

[2] Zhan, N.#,Zhang, L.#, Yang, H., Zheng, Y., Wei, X., Wang, J., & Shan, A. (2021). Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris. Microbial Cell Factories, 20(1).https://doi.org/10.1186/s12934-021-01635-x

[3]Zhang, L. C., Guo, T., Zhan, N., Sun, T. T., & Shan, A. S. (2021). The Effects of the antimicrobial peptide WK3 on diarrhea, growth performance and intestinal health of weaned piglets challenged with enterotoxigenic Escherichia coli K88. Food & Nutrition Research, 65.https://doi.org/ARTN344810.29219/fnr.v65.3448

[4]Zhang, L. C., Wei, D. D., Zhan, N., Sun, T. T., Shan, B. D., & Shan, A. S. (2020). Heterologous expression of the novel α-helical hybrid peptide PR-FO in Bacillus subtilis. Bioprocess and Biosystems Engineering, 43(9), 1619-1627.https://doi.org/10.1007/s00449-020-02353-1

[5]Zhang, L., Li, X., Zhan, N., Sun, T., Li, J., & Shan, A. (2020). Maltose Induced Expression of Cecropin AD by SUMO Technology in Bacillus subtilis WB800N. The Protein Journal, 39(4), 383-391.https://doi.org/10.1007/s10930-020-09908-x

[6]Zhang, L. C., Li, G. Q., Zhan, N., Sun, T. T., Cheng, B. J., Li, Y. B., & Shan, A. S. (2019). Expression of a Pseudomonas aeruginosa-targeted antimicrobial peptide T9W in Bacillus subtilis using a maltose-inducible vector. Process Biochemistry, 81, 22-27.https://doi.org/10.1016/j.procbio.2019.03.008

[7]Zhang, L. C., Li, X. D., Wei, D. D., Wang, J., Shan, A. S., & Li, Z. Y. (2015). Expression of plectasin in Bacillus subtilis using SUMO technology by a maltose-inducible vector. Journal of Industrial Microbiology & Biotechnology, 42(10), 1369-1376.https://doi.org/10.1007/s10295-015-1673-y

[8] 程宝晶,李仲玉,张丽聪*.霉菌毒素对畜禽危害及其中毒防治手段的研究进展.饲料工业, 2025, 46, (12): 127-135. DOI:10.13302/j.cnki.fi.2025.12.019.

[9]张丽聪,张凌玮,刘玥垚等.抗菌肽重组制备:在微生物工厂中产量优化策略.微生物学通报, 2025, 52, (10): 4424-4440. DOI:10.13344/j.microbiol.china.250175.

在研课题

1. 国家自然科学基金青年基金，基于螺旋束基序开发“烘焙-沉淀”纯化技术重组制备抗酶解抗菌肽，主持，2025-2027

2. 黑龙江省自然科学基金联合引导项目，基于螺旋束基序开发“烘焙-沉淀“纯化技术重组制备抗酶解抗菌肽，主持，2023-2026