1.教育状况

2010.09-2014.11：加拿大多伦多大学生物学和细胞分子生物学，学士

2015.09-2018.06：东北林业大学特种经济动物饲养，硕士研究生

2018.09-2021.06：东北农业大学临床兽医学，博士研究生

2.工作经历

2022.10-至今：东北农业大学动物科学技术学院 讲师，硕士研究生导师

代表性论文（第一作者或通讯作者）：

（本人名字处 可标粗）

[1] Miao Zhiruo, Wang Wei, Miao Zhiying, Cao Qiyuan, Xu Shiwen*. Role of Selenoprotein W in participating in the progression of non-alcoholic fatty liver disease. Redox Biol. 2024, 103114. (IF:11.9, 中科院1区Top)

[2] Miao Zhiruo, Zhao Peiyu, Cao Qiyuan, Ding Ye, Xu Shiwen*. Protective effect of melatonin on imidacloprid-induced pyroptosis and ferroptosis by mediating peptidoglycan in the gut of the common carp (Cyprinus carpio). Pestic Biochem Physiol. 2024, 202:105935. (IF:4.0, 中科院1区Top)

[3] Miao Zhiruo, Miao Zhiying, Liu Min, Xu Shiwen*. Melatonin ameliorates imidacloprid-induced intestinal injury by negatively regulating the PGN/P38MAPK pathway in the common carp (Cyprinuscarpio). Fish Shellfish Immunol. 2022, 131:1063-1074. (IF:3.9, 中科院2区Top)

[4] Miao Zhiruo, Miao Zhiying, Wang Shenchen, Wu Hao, Xu Shiwen*. Exposure to imidacloprid induce oxidative stress, mitochondrial dysfunction, inflammation, apoptosis and mitophagy via NF-kappaB/JNK pathway in grass carp hepatocytes. Fish Shellfish Immunol. 2022, 120:674-685. (IF:3.9, 中科院2区Top)

[5] Miao Zhiruo, Miao Zhiying, Wang Shenchen, Shi Xu, Xu Shiwen*. Quercetin antagonizes imidacloprid-induced mitochondrial apoptosis through PTEN/PI3K/AKT in grass carp hepatocytes. Environ Pollut. 2021, 290:118036. (IF=7.3，中科院2区Top)

[6] Miao Zhiruo, Miao Zhiying, Shi Xu, Wu Hao, Yao Yujie, Xu Shiwen*. The antagonistic effect of selenium on lead-induced apoptosis and necroptosis via P38/JNK/ERK pathway in chicken kidney. Ecotoxicol Environ Saf. 2022, 231:113176. (IF=6.1，中科院2区)

[7] Wang Wei, Miao Zhiruo, Qi Xue, Wang Bing, Liu Qingqing, Shi Xu, Xu Shiwen*.. LncRNA Tug1 relieves the steatosis of SelenoF-knockout hepatocytes via sponging miR-1934-3p. Cell Biol Toxicol. 2023, 39(6):3175-3195. (IF=5.9，中科院2区)

[8] Miao Zhiying, Miao Zhiruo, Teng Xiaohua, Xu Shiwen*. Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis. Environ Pollut. 2023, 317:120730. (IF=7.3，中科院2区Top)

[9] Miao Zhiying, Miao Zhiruo, Teng Xiaohua, Xu Shiwen*. Chlorpyrifos triggers epithelioma papulosum cyprini cell pyroptosis viamiR-124-3p/CAPN1 axis, J Hazard Mater. 2022, 424(Pt A):127318. (IIF=11.3，中科院1区Top)

在研课题

1.国家自然科学基金青年科学基金项目，30万元，2025.01-2027.12，主持

2.黑龙江省自然科学基金联合引导项目，10万元，2024.12-2027.12，主持

3.黑龙江省博士后面上资助项目，10万元，2024.12-2027.12，主持

4.东北农业大学“第五层次 B 类人才”项目，20万元，2022.10-2025.10，主持

5. 国家自然科学基金区域联合重点基金项目，252万元 2023.01-2026.12，参与