1． 教育状况

2006.09-2011.06：东北农业大学，动物医学专业，学士

2011.09-2014.06：东北农业大学，预防兽医学专业，硕士研究生

2014.09-2017.06：东北农业大学，预防兽医学专业，博士研究生

2．工作经历

2017.10-2021.09：东北农业大学动物科学技术学院 水产养殖系，讲师

2021.09-2024.12：东北农业大学动物科学技术学院 水产养殖系，副教授（硕士生导师）

2024.12-至今：东北农业大学动物科学技术学院 水产养殖系，副教授（博士生导师）

3. 著作论文

代表性论文（一作/通讯作者）

1. Huilin He, Ruixue Feng, Siyi Guo, Bing Han, Jinshan Huang, Xu Lin, Jiyuan Yin, Defeng Zhang, Min Liui*, Wen Shi*. Development of a Sensitive Real-Time PCR Method for Detection of Carp Oedema Virus, Journal of Fish Diseases, 2025; 0:e70027. （IF:2.2, 中科院3区，JCR 1区）

2.施 雯，郭思伊，管雪婷，窦秀静，张 攀，姚玉昌，董 娜.“双一流”建设背景下专业课程思政教学实践［J］. 黑龙江动物繁殖，2025，33（3）：81-85，89.（省级优秀期刊）

3.Wen Shi, Bing Han, Huilin He, Ruixue Feng, Siyi Guo, Xuanyu Ren, Jinshan Huang, Xu Lin, Jiyuan Yin, Xiaonan Lv, Min Liu*, Identification of a novel strain of carp edema virus affecting Songpu mirror carp in Liaoning, China, Aquaculture,2025, 599, 742151. (IF:5.135, 中科院1区)

4. 施雯*,张艳姿,韩冰,刘忠华,马海鹍,辛杭书,姚玉昌.短视频在动物免疫学课程中的教学创新探索与实践.中国免疫学杂志2024.40 (12):2642-2645+2649.（中文核心，CSCD前35%）

5. Shi Wen, Wang Na, Han Bing, Zhang Mengmeng, Shi Yanxue, Zhao Dandan, Zhang Yanzi, Zhao Fengxia, Guan Xueting, Huang Jinshan, Liu Min*. Fish DDX3 enhances antiviral immunity by up-regulating antiviral interferon responses. Aquaculture 2023, 566, 739176. (IF:5.135, 中科院1区)

6. Shuai Gao, Bing Han, Baoxing Xu, Na Wang, Yanru Zhang, Xuefei Liu, Mengmeng Zhang, Guanbo Wang, Xueting Guan, Jinshan Huang, Min Liu, Wen Shi*. SAV Nsp2 regulates NF-κB signaling to induce inflammatory responses by targeting host DDX3, Developmental & Comparative Immunology, 2023, 140：104612. (中科院2区，JCR1区，IF3.605)

7. Shuai Gao, Xuefei Liu, Bing Han, Na Wang, Xiaonan Lv, Xueting Guan, Gefeng Xu, Jinshan Huang, Wen Shi*, Min Liu*. Salmonid alphavirus non-structural protein 2 is a key protein that activates the NF-κB signaling pathway to mediate inflammatory responses. Fish & Shellfish Immunology, 2022, 129: 182-190.(IF:4.622, 中科院1区)

8. Yanru Zhang, Jinhui Sun, Yanxue Shi, Xuefei Liu, Mengmeng Zhang, Baoxing Xu, Jian Song, Zhenguo Song, Xueting Guan, Wen Shi*, Min Liu*. Oncorhynchus mykiss OmTRIM25 activates the interferon-1 pathway and positively regulates the antiviral innate immune response to infectious hematopoietic necrosis virus. Aquaculture, 2022,560，738435. https://doi.org/10.1016/j.aquaculture.2022.738435 (IF:5.135, 中科院1区)

9. Shuai Gao，Na Wang，Jiawei Yang，Jinhui Sun，Yuting Wang，Dong Xia，Jingwen Tian，Yuntong Zhao，Ying Feng，Ying Zhou，Xueting Guan，Wen Shi*，Min Liu*.Development and evaluation of indirect double-antibody sandwich ELISA for rapid detection of Salmonid Alphavirus using Baculoviridae expressed E1 Protein.Aquaculture,2021,544，737081. (IF:5.135, 中科院1区)

10. 施雯,赵凤霞,张福婷,刘忠华,马海鹍,辛杭书,姚玉昌,刘敏.翻转课堂在水产动物免疫学上的应用探究[J].黑龙江畜牧兽医,2021(16):135-138.（中文核心）

11. Shi Wen, Jia Shuo, Guan Xueting, Yao Xin, Pan Ronghui, Huang Xinning, Ma Yingying, Wei Jing, Xu Yigang*. A survey of jaagsiekte sheep retrovirus (JSRV) infection in sheep in the three northeastern provinces of China. Arch Virol 2021. 166:831-840. (IF：2.685, 中科院4区)

12. Xiaojing Hua, Ying Zhou, Ying Feng, Kexin Duan, Xuanyu Ren, Jinhui Sun, Shuai Gao, Na Wang, Jiahui Li, Jiawei Yang, Dong Xia, Chunyue Li, Xueting Guan, Shi Wen*, Liu Min*. Oral vaccine against IPNV based on antibiotic-free resistance recombinant Lactobacillus casei expressing CK6-VP2 fusion protein,Aquaculture,2021,535,736425. (IF:5.135, 中科院1区)

13. Chen Yaping, Hua Xiaojing, Ren Xuanyu, Duan Kexin, Gao Shuai, Sun Jinhui, Feng Ying, Zhou Ying, Guan Xin, Li Dechuan, Wang Na, Li Jiahui, Yang Jiawei, Xia Dong, Shi Wen*, Liu Min*. Oral immunization with recombinant Lactobacillus casei displayed AHA1-CK6 and VP2 induces protection against infectious pancreatic necrosis in rainbow trout (Oncorhynchus mykiss). Fish Shellfish Immunol 2020. 100:18-26. (IF:4.622中科院1区)

14. Guo Mengting#, Shi Wen#, Wang Yanxue, Wang Yuting, Chen Yaping, Li Dechuan, Ren Xuanyu, Hua Xiaojing, Tang Lijie, Li Yijing, Liu Min*. Recombinant infectious hematopoietic necrosis virus expressing infectious pancreatic necrosis virus VP2 protein induces immunity against both pathogens. Fish Shellfish Immunol 2018.78:187-194. (IF:4.622中科院1区)

15. Iram Maqsood #, Wen Shi #, Xiaona Wang, Bing Han, Haiyuan Zhao, Abbas Muhammad Nadeem, Bukhari syed Moshin, Kausar Saima, Shah Syed Jamal, Mufti Farees ud Din, Yigang Xu, Lijie Tang*, Yijing Li*. Immunogenicity and protective efficacy of orally administered recombinant Lactobacillus plantarum expressing VP2 protein against IBDV in chicken. Journal of Applied Microbiology 2018. 125, (6), 1670-1681. (IF:4.059中科院3区)

16. Shi Wen, Fan Wenlu, Bai Jing, Tang Yandong, Wang Li, Jiang Yanping, Tang Lijie, Liu Min, Xu Yigang*, Li Yijing*. TMPRSS2 and MSPL facilitate trypsin-independent porcine epidemic diarrhea virus replication in Vero cells. Viruses 2017, 9(5), 114. (IF:5.818中科院2区)

17. Shi Wen, Jia Shuo, Zhao Haiyuan, Yin Jiyuan, Wang Xiaona, Yu Meiling, Ma Sunting, Wu Yang, Chen Ying, Fan Wenlu, Xu Yigang*, Li Yijing*.Novel Approach for Isolation and Identification of Porcine Epidemic Diarrhea Virus (PEDV) Strain NJ Using Porcine Intestinal Epithelial Cells. Viruses 2017, 9(1), 19. (IF:5.818 中科院2区)

18. Shi Wen, Song Aochen, Gao Shuai, Wang Yuting, Tang Lijie, Xu Yigang, Ren Tong, Li Yijing, Liu Min*, Rapid and sensitive detection of salmonid alphavirus using TaqMan real-time PCR.Molecular and cellular probes 2017 34, 13-20. (IF:3.285 中科院4区)

19. Shi Wen, Wang Yuting, Ren Xuanyu, Gao Shuai, Hua Xiaojing, Guo Mengting, Tang Lijie, Xu Yigang, Ren Tong, Li Yijing, Liu Min*, EvaGreen-based real-time PCR assay for sensitive detection of salmonid alphavirus. Molecular and cellular probes 2018 (39):7-13. (IF:3.285 中科院4区)

4. 在研课题

1. 国家自然科学基金面上项目，51万元，2026.01-2029.12，主持人

2. 企业横向课题，106万元，2025.04-2030.04，主持人

3. 国家自然科学基金青年科学基金项目，30万元，2025.01-2027.12，主持人

4. 黑龙江省自然科学基金优秀青年项目，10万元，2024.12-2027.12，主持人

5. 中国博士后科学基金面上资助项目，8万元，2024.01-2026.12，主持人

6. 黑龙江省博士后面上资助项目，10万元，2024.01-2026.12，主持人

7. 东农学者计划“学术骨干”项目，10万元，2022.07-2025.07，主持人

8. 东北农业大学ESI国际高影响力论文合作项目，1万元，2022.09-2024.09，主持人

9. 黑龙江省联合引导项目，10万元，2019.07-2022.07，主持人

10.东农学者计划“青年才俊”项目，6万元，2018.11-2021.09，主持人

5. 授权专利：

1. 一种鲤浮肿病毒体外分离培养方法（1/3），2022.7.12，中国，专利号：ZL 202210810758.6，授权公告号：CN 114874998 B

2.一种用于猫传染性腹膜炎病毒检测的RT-PCR引物组（4/6），中国，专利号：CN107586884B