1． 教育状况

2006.09-2011.06：东北农业大学，动物医学专业，学士

2011.09-2014.06：东北农业大学，预防兽医学专业，硕士研究生

2014.09-2017.06：东北农业大学，预防兽医学专业，博士研究生

2．工作经历

2017.10-2021.09：东北农业大学动物科学技术学院 水产养殖系，讲师

2021.09-至今：东北农业大学动物科学技术学院 水产养殖系，副教授（硕士研究生导师）

著作论文

代表性论文（一作/通讯作者）

1.Shi Wen,Wang Na, Han Bing, Zhang Mengmeng, Shi Yanxue, Zhao Dandan, Zhang Yanzi, Zhao Fengxia, Guan Xueting, Huang Jinshan, Liu Min^*. Fish DDX3 enhances antiviral immunity by up-regulating antiviral interferon responses. Aquaculture 2023, 566, 739176.(IF:5.135,中科院1区)

2.Shuai Gao, Bing Han, Baoxing Xu, Na Wang, Yanru Zhang, Xuefei Liu, Mengmeng Zhang, Guanbo Wang, Xueting Guan, Jinshan Huang, Min Liu,Wen Shi^*. SAV Nsp2 regulates NF-κB signaling to induce inflammatory responses by targeting host DDX3, Developmental & Comparative Immunology, 2023, 140：104612.(中科院2区，JCR1区，IF3.605)

3.Shuai Gao, Xuefei Liu, Bing Han, Na Wang, Xiaonan Lv, Xueting Guan, Gefeng Xu, Jinshan Huang,Wen Shi^*, Min Liu^*. Salmonid alphavirus non-structural protein 2 is a key protein that activates the NF-κB signaling pathway to mediate inflammatory responses. Fish & Shellfish Immunology, 2022, 129: 182-190.(IF:4.622,中科院1区)

4.Yanru Zhang, Jinhui Sun, Yanxue Shi, Xuefei Liu, Mengmeng Zhang, Baoxing Xu, Jian Song, Zhenguo Song, Xueting Guan,Wen Shi*, Min Liu*. Oncorhynchus mykiss OmTRIM25 activates the interferon-1 pathway and positively regulates the antiviral innate immune response to infectious hematopoietic necrosis virus. Aquaculture, 2022,560，738435. https://doi.org/10.1016/j.aquaculture.2022.738435(IF:5.135,中科院1区)

5.Shuai Gao，Na Wang，Jiawei Yang，Jinhui Sun，Yuting Wang，Dong Xia，Jingwen Tian，Yuntong Zhao，Ying Feng，Ying Zhou，Xueting Guan，Wen Shi^*，Min Liu^*.Development and evaluation of indirect double-antibody sandwich ELISA for rapid detection of Salmonid Alphavirus using Baculoviridae expressed E1 Protein.Aquaculture,2021,544，737081.(IF:5.135,中科院1区)

6.施雯,赵凤霞,张福婷,刘忠华,马海鹍,辛杭书,姚玉昌,刘敏.翻转课堂在水产动物免疫学上的应用探究[J].黑龙江畜牧兽医,2021(16):135-138.（中文核心）

7.Shi Wen,Jia Shuo, Guan Xueting, Yao Xin, Pan Ronghui, Huang Xinning, Ma Yingying, Wei Jing, Xu Yigang^*. A survey of jaagsiekte sheep retrovirus (JSRV) infection in sheep in the three northeastern provinces of China. Arch Virol 2021. 166:831-840.(IF：2.685,中科院4区)

8.Xiaojing Hua, Ying Zhou, Ying Feng, Kexin Duan, Xuanyu Ren, Jinhui Sun, Shuai Gao, Na Wang, Jiahui Li, Jiawei Yang, Dong Xia, Chunyue Li, Xueting Guan,Shi Wen^*, Liu Min^*. Oral vaccine against IPNV based on antibiotic-free resistance recombinant Lactobacillus casei expressing CK6-VP2 fusion protein,Aquaculture,2021,535,736425.(IF:5.135,中科院1区)

9.Chen Yaping, Hua Xiaojing, Ren Xuanyu, Duan Kexin, Gao Shuai, Sun Jinhui, Feng Ying, Zhou Ying, Guan Xin, Li Dechuan, Wang Na, Li Jiahui, Yang Jiawei, Xia Dong,Shi Wen^*, Liu Min^*. Oral immunization with recombinant Lactobacillus casei displayed AHA1-CK6 and VP2 induces protection against infectious pancreatic necrosis in rainbow trout (Oncorhynchus mykiss). Fish Shellfish Immunol 2020. 100:18-26. (IF:4.622中科院1区)

10.Guo Mengting^#,Shi Wen^#, Wang Yanxue, Wang Yuting, Chen Yaping, Li Dechuan, Ren Xuanyu, Hua Xiaojing, Tang Lijie, Li Yijing, Liu Min^*. Recombinant infectious hematopoietic necrosis virus expressing infectious pancreatic necrosis virus VP2 protein induces immunity against both pathogens. Fish Shellfish Immunol 2018.78:187-194.(IF:4.622中科院1区)

11.Iram Maqsood^#,Wen Shi^#, Xiaona Wang, Bing Han, Haiyuan Zhao, Abbas Muhammad Nadeem, Bukhari syed Moshin, Kausar Saima, Shah Syed Jamal, Mufti Farees ud Din, Yigang Xu, Lijie Tang^*, Yijing Li^*_.Immunogenicity and protective efficacy of orally administered recombinant Lactobacillus plantarum expressing VP2 protein against IBDV in chicken. Journal of Applied Microbiology 2018. 125, (6), 1670-1681. (IF:4.059中科院3区)

12.Shi Wen, Fan Wenlu, Bai Jing, Tang Yandong, Wang Li, Jiang Yanping, Tang Lijie, Liu Min, Xu Yigang^*, Li Yijing^*. TMPRSS2 and MSPL facilitate trypsin-independent porcine epidemic diarrhea virus replication in Vero cells. Viruses 2017, 9(5), 114. (IF:5.818中科院2区)

13.Shi Wen,Jia Shuo, Zhao Haiyuan, Yin Jiyuan, Wang Xiaona, Yu Meiling, Ma Sunting, Wu Yang, Chen Ying, Fan Wenlu, Xu Yigang^*, Li Yijing^*.Novel Approach for Isolation and Identification of Porcine Epidemic Diarrhea Virus (PEDV) Strain NJ Using Porcine Intestinal Epithelial Cells. Viruses 2017, 9(1), 19.(IF:5.818中科院2区)

14.Shi Wen, Song Aochen, Gao Shuai, Wang Yuting, Tang Lijie, Xu Yigang, Ren Tong, Li Yijing, Liu Min^*, Rapid and sensitive detection of salmonid alphavirus using TaqMan real-time PCR.Molecular and cellular probes 2017 34, 13-20.(IF:3.285中科院4区)

15.Shi Wen,Wang Yuting, Ren Xuanyu, Gao Shuai, Hua Xiaojing, Guo Mengting, Tang Lijie, Xu Yigang, Ren Tong, Li Yijing, Liu Min^*, EvaGreen-based real-time PCR assay for sensitive detection of salmonid alphavirus. Molecular and cellular probes 2018 (39):7-13.(IF:3.285中科院4区)

在研课题

1.中国博士后科学基金面上资助项目（2023MD744174），8万元，2024.01-2026.12，主持

2.黑龙江省博士后面上资助项目（LBH-Z23089），10万元，2024.01-2026.12，主持

3.东农学者计划“学术骨干”项目，10万元，2022.07-2025.07，主持

4.东北农业大学ESI国际高影响力论文合作项目，1万元，2022.09-2024.09，主持

5.黑龙江省联合引导项目（LH2019C028），10万元，2019.07-2022.07，主持

6.东农学者计划“青年才俊”项目（18QC38），6万元，2018.11-2021.09，主持